Carbon-impregnated IMPRA^® Carboflo^® vascular grafts are designed for peripheral vascular disease and hemodialysis access. These vascular grafts are an innovation in surface dynamics, and studies demonstrate the advantage of innovative carbon technology.

Scientific Studies

• Studies demonstrate the advantage of innovative carbon technology.
• Carbon-impregnated IMPRA^® Carboflo^® vascular grafts, when compared to a similar graft without carbon, are associated with a decrease in platelet adhesion and fibrin deposition—but are not associated with any change in patency or reduced embolism in animal studies.
• In preclinical animal studies:
  • The carbon lining significantly decreases platelet accumulation.¹
  • Six times greater platelet deposition results with standard PTFE grafts vs. carbon-lined grafts.²
  • Carbon-coated PTFE grafts show statistically greater thrombus-free area.³

Carbon Technology with Several IMPRA^® Grafts

• Carbon-impregnated ePTFE graft technology is offered with several IMPRA^® prosthetic grafts, including the following:
• IMPRA^® Carboflo^® vascular grafts—for peripheral vascular disease and hemodialysis access.
• DISTAFLO^® bypass grafts—designed to improve arterial bypass patency.
• VENAFLO^™ vascular grafts—developed specifically for hemodialysis to address intimal hyperplasia.

1. Tsuchida H., Cameron BL, Marcus CS, Wilson SE. Modified polytetrafluoroethylene: Indium III-labeled platelet deposition on carbon-lined and high-porosity polytetrafluoroethylene grafts. J Vasc Surg. 1992; 16 (No. 4): 643-650.
2. Babatasi G, Bara I, Galateau F, et al. An animal model for the evaluation of graft thrombosis in the acute phase on carbon-lined PTFE prosthesis. Int J Art Org. 1994; 17 (No. 6): 643-650.
3. Schmidt SP, Evancho MM. A study of patency and durability of Impra, Inc. carbon-coated synthetic prosthesis in dogs. Data on file.